Topical and oral medications custom curated by your dermatologist.

Explore our treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

Our proprietary custom topical formula comes packed with prescription-grade ingredients in a moisturizing lotion with 4% niacinamide, aloe and vitamin E. Apostrophe’s topical medication blends seamlessly into your skincare routine– no more weird goopy aluminum tubes. All that tailored to you by your board-certified dermatologist.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. We offer the widest range of prescription ingredients and strengths so our doctors can create the formula that’s perfect for your skin. From the most sensitive skin to the most severe acne, our custom topical formula has you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

Our nourishing texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Apostrophe Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Orals are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your doctor will only prescribe these if they feel you’ll get better results.

Learn more about our antibiotics

Hormonal treatment

This treatment is for women who experience jawline breakouts that are caused by hormonal imbalances. Your doctor will only prescribe this if they feel you’re a good candidate.

Learn more about our hormonal treatments

Better, together.

Your Apostrophe treatment plan may contain several of these power-packed medications. Your dermatologist will design your medication to work synergistically together so you can get the best possible outcomes.

“Acne medications work best in combination since we’re able to fight acne from different angles. Only topical treatments target the root cause of acne, the clogged pore, but oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Aimee paik, md

Real Patients,
real results.

Read reviews of our topical and oral medications below.

5.00/5 based on 5 reviews.
Caret iconBlack upwards facing triangle to reference things above or scroll to the top of page.
Caret iconBlack upwards facing triangle to reference things above or scroll to the top of page.
790 reviews
10/20/2021

My skin definitely looks lighter - especially the areas with dark spots and sun damage. I still have a lot of dark spots though and wish they were fading faster.

Pearl
10/20/2021
10/20/2021

I was breaking out a lot. It's been about 2-3wks of using this product and have had no big flareups. I purged a bit; not as bad as I expected. Watching to see how it gets better.

Pearl
10/20/2021
10/20/2021

So far I've seen better skin glow and fewer breakouts!

Kevin
10/20/2021
10/19/2021

I love this formula! I have been using it in tandem with another from Apostrophe. I haven't had any side effects and my skin looks fantastic. I have never used a topical treatment that cleared my skin like this and didn't burn my sensitive. I have had a fantastic experience with Apostrophe thus far.

Ashley
10/19/2021
10/15/2021

It seems to be working for me! Thanks!

Ian
10/15/2021
10/15/2021

The only thing that worked on my acne before was anitbiotics, so I was super excited to try something geared towards hormonal acne. I must say, the dosage was a bit high for me and I did have some side-effects (dizziness and fatigue especially), but the Apostrophe team was quick to get back to me and told me to decrease my dose. After that, it's been a really smooth ride with spiro. I haven't had a painful, cystic breakout since starting this medication and I'm super excited to see what my skin looks like in a few months!

Linsey
10/15/2021
10/15/2021

I've been wanting to try Tret for a long time, and I'm so happy I found this company. I'm dealing with hormonal acne at 27 years old. I cannot remember the last time I had acne this bad! This has been the only thing that's worked for me (besides the spironolactone also from Apostrophe!). It's super potent, though and I could've started out slower. I'm so excited to keep using this to see how good my skin can get!

Linsey
10/15/2021
10/15/2021

I contacted Apostrophe for a refill of my tretinoin script. The customer service, speed, cost, etc. has been awesome and I plan to use this amazing service for a long time :). I was using .025% and was up'd to .05%. It was def. stronger and I had to go down to every-other-day use (for now). With most tretinoin, it was a bit irritating to my skin at first, but this is totally normal and I knew what to expect...stick with it! Now, my skin is soft, I'm seeing more clarity and I'm glad the dermatologist recommended the higher concentration. I do wish it came in an aluminum tube like the script vs the plastic pump (I just prefer cosmetics this way)...but not a deal breaker ;) and I understand it assists with "dosing" the right amount. Overall, I've been very happy with this product and Apostrophe! Thank you!

Corrie
10/15/2021
10/12/2021

It makes my face really soft, which is awesome, but I don't think the formula is strong enough for what my face has going on right now

Jessica
10/12/2021
10/11/2021

I've been taking the Doxycycline for about three weeks now and haven't experienced any adverse side effects. I take it at lunch right before I eat a full meal with a 16 oz. bottle of water. It appears to be decreasing the purging process of the acne Tretinoin + Azelaic Acid Formula treatment.

Virginia
10/11/2021