Apostrophe Oral medication and topical medication bottles stacked on shapes
Apostrophe Oral medication and topical medication bottles stacked on shapes
Apostrophe Oral medication and topical medication bottles stacked on shapes

Topical and oral medications custom curated by your dermatologist.

Explore our treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

Our proprietary custom topical formula comes packed with prescription-grade ingredients in a moisturizing lotion with 4% niacinamide, aloe and vitamin E. Apostrophe’s topical medication blends seamlessly into your skincare routine– no more weird goopy aluminum tubes. All that tailored to you by your board-certified dermatologist.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. We offer the widest range of prescription ingredients and strengths so our doctors can create the formula that’s perfect for your skin. From the most sensitive skin to the most severe acne, our custom topical formula has you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

Our nourishing texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Apostrophe Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Orals are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your doctor will only prescribe these if they feel you’ll get better results.

Learn more about our antibiotics

Hormonal treatment

This treatment is for women who experience jawline breakouts that are caused by hormonal imbalances. Your doctor will only prescribe this if they feel you’re a good candidate.

Learn more about our hormonal treatments

Better, together.

Your Apostrophe treatment plan may contain several of these power-packed medications. Your dermatologist will design your medication to work synergistically together so you can get the best possible outcomes.

“Acne medications work best in combination since we’re able to fight acne from different angles. Only topical treatments target the root cause of acne, the clogged pore, but oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Aimee paik, md

Real Patients,
real results.

Read reviews of our topical and oral medications below.

5.00/5 based on 5 reviews.
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Caret iconBlack upwards facing triangle to reference things above or scroll to the top of page.
941 reviews
4/24/2022

I so far love this tretinoin formula, and I see it as an upgrade of the previous formulas I'm used to. This one sinks right into the skin, and absorbs well. The only con for me -- is the price. I am under special circumstances though, so if you can afford it, I say do it.

Yaniyah
4/24/2022
4/21/2022

this cream has cleared up my acne and made my skin glow, literally! I never experienced any side effects personally and have been loving the new look my skin has. Definitely something I will continue to use to keep my acne away

Clover
4/21/2022
4/21/2022

This is my first time using Apostrophe and they made it so easy to get medication that I would normally require a doctor and pharmacy visit. My skin has cleared up in just a couple weeks and I couldn't be happier. It also is great that it's a two-month supply versus one month, which is what you usually get visiting a doctor. Thanks Apostrophe!

Samantha
4/21/2022
4/20/2022

No side effects thus far. I'm starting to see subtle changes but I think it's too early to see any huge changes.

Rebecca
4/20/2022
4/20/2022

I have used Tazorac in the past and this product is just as effective. The niacinamide is a nice addition to the formula and has a subtle smoothing, brightening effect. I do wish there was a .1% strength for this formula as it has a stronger line softening effect for me, but the .05% is working great on my acne.

Alexandra
4/20/2022
4/18/2022

My skin is much brighter and even. I think I'm only at 2wks.

Peolia
4/18/2022
4/16/2022

It seems to be workin well! I wish I wouldve discovered apostrophe a long time ago!

Stacy
4/16/2022
4/14/2022

I was previously visiting an in-office dermatologist for pretty much the same products. Not only is this much easier to order, it's easier to use since its all formulated into one cream. I love it!

Hannah
4/14/2022
4/13/2022

I've seen a bit of a difference with my skin so far. It's been a really stressful time, and I think my skin should be so much worse than it is right now. I have switched to using this during the day instead of at night to see if it helps control oil a bit, but I haven't really noticed much of a difference.

Amanda
4/13/2022
4/13/2022

Only a few weeks in but I'm liking it! I was already on a lower dose of the Tretinoin and the higher dose works better. Not sure about the Spironolactone yet.

Abigail
4/13/2022