Topical and oral medications custom curated by your dermatologist.

Explore our treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

Our proprietary custom topical formula comes packed with prescription-grade ingredients in a moisturizing lotion with 4% niacinamide, aloe and vitamin E. Apostrophe’s topical medication blends seamlessly into your skincare routine– no more weird goopy aluminum tubes. All that tailored to you by your board-certified dermatologist.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. We offer the widest range of prescription ingredients and strengths so our doctors can create the formula that’s perfect for your skin. From the most sensitive skin to the most severe acne, our custom topical formula has you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

Our nourishing texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Apostrophe Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Orals are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your doctor will only prescribe these if they feel you’ll get better results.

Learn more about our antibiotics

Hormonal treatment

This treatment is for women who experience jawline breakouts that are caused by hormonal imbalances. Your doctor will only prescribe this if they feel you’re a good candidate.

Learn more about our hormonal treatments

Better, together.

Your Apostrophe treatment plan may contain several of these power-packed medications. Your dermatologist will design your medication to work synergistically together so you can get the best possible outcomes.

“Acne medications work best in combination since we’re able to fight acne from different angles. Only topical treatments target the root cause of acne, the clogged pore, but oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Aimee paik, md

Real Patients,
real results.

Read reviews of our topical and oral medications below.

5.00/5 based on 5 reviews.
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765 reviews
9/22/2021

I'm pleased with the results of the product, but couple of things I'm disappointed with. The pump didn't work when I first tried to use it. I have to unscrew the cap to get the product out. This is a pain and messy to use. Also, my skin is very oily for most of the day. I like the dry feel of my skin rather than this oily sticky face feel. One more thing. Not sure if the product will last until my next shipment. Better ship one week earlier. Other than that I like the product. Thank you, Denny

Denny
9/22/2021
9/22/2021

I've been taking Spiro for years. I recently switched to Apostrophe instead of my local derm and my skin is still doing well on this medication. I still get a few pimples every month especially around my period but my skin is mostly clear. I get cystic acne MUCH less. Mostly smaller pimples. The one downside to this medication is you will pee a lot more than usual when taking this drug. I hope with topicals I can eventually go off this oral due to side effects.

Kristen
9/22/2021
9/22/2021

Here are the things that have changed since I first started this formula. However, correlation does not equal causation so take what you will from my review. I have not switched to using this every night, but still at a pace of every other night: - Less breakouts but still breaking out - When I do break out, the acne seems to go away quicker and is smaller. I used to go through pimple patches like crazy. Now I am using maybe one a week - No noticeable changes to previous acne scars I am determined to stick with this until it runs out though so good luck!

Hmellisa
9/22/2021
9/22/2021

I have had stubborn acne for my entire life. Even after Accutane, I wasn't free from it. Topical Tretinoin + Clindamycin really cleared my skin and have kept me acne free for the first time in my life. It's truly amazing

Joshua
9/22/2021
9/22/2021

I have been using it for a month and my skin looks so much better already. The "mascne" are finally under control. I love it!

Gaia
9/22/2021
9/21/2021

Using the way as recommended along with other items as suggested. No results or signs of improvement. Going to stick it out until 3 months and hope for better ending.

Renee
9/21/2021
9/21/2021

I love the tretinoin it is causing the old skin to peel off leaving a better complection. Thank you.

Susan
9/21/2021
9/21/2021

My skin started to clear up after 2 weeks and it has been glowy, clear, and smooth ever since with minor breakouts here and there.

Addyston
9/21/2021
9/19/2021

I was at a breaking point with my cystic acne. I am so glad I ordered this! It has been a few weeks, but I do not have any new breakouts and the old ones are healing well. My skin did dry out, so be sure to moisturize!

Kadee
9/19/2021
9/17/2021

Had immediate results with these products! So very happy with how my skin looks! Thank you thank you!

Kristen
9/17/2021