Topical and oral medications custom curated by your dermatologist.

Explore our treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

Our proprietary custom topical formula comes packed with prescription-grade ingredients in a moisturizing lotion with 4% niacinamide, aloe and vitamin E. Apostrophe’s topical medication blends seamlessly into your skincare routine– no more weird goopy aluminum tubes. All that tailored to you by your board-certified dermatologist.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. We offer the widest range of prescription ingredients and strengths so our doctors can create the formula that’s perfect for your skin. From the most sensitive skin to the most severe acne, our custom topical formula has you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

Our nourishing texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Apostrophe Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Orals are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your doctor will only prescribe these if they feel you’ll get better results.

Learn more about our antibiotics

Hormonal treatment

This treatment is for women who experience jawline breakouts that are caused by hormonal imbalances. Your doctor will only prescribe this if they feel you’re a good candidate.

Learn more about our hormonal treatments

Better, together.

Your Apostrophe treatment plan may contain several of these power-packed medications. Your dermatologist will design your medication to work synergistically together so you can get the best possible outcomes.

“Acne medications work best in combination since we’re able to fight acne from different angles. Only topical treatments target the root cause of acne, the clogged pore, but oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Aimee paik, md

Real Patients,
real results.

Read reviews of our topical and oral medications below.

5.00/5 based on 5 reviews.
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633 reviews
6/11/2021

I have been using this for almost 3 weeks now. I haven't noticed any over-the-top dryness or other side effects. My acne hasn't improved yet but sometimes I notice a subtle glow that I wonder if it's from the tretinoin. I'm optimistic to keep using it.

Alison
6/11/2021
6/11/2021

I have been using this almost 3 weeks now. First week I started at half dose and now take 1 pill/day in the evenings. I take in the evenings because I wanted to avoid daytime dizziness. I do sometimes feel dizzy though (actually, more during the day than in the evening... so maybe I need to change the schedule haha) but otherwise haven't had any other noticeable side effects.

Alison
6/11/2021
6/11/2021

I've only been using this product for a few months, but it seems to be effective! Terrible smell, however...

Sydney
6/11/2021
6/10/2021

First 3 weeks, My skin gets worse I see more break outs on my skin but its been almost 1month my skin starts to calming I don't see big difference yet but I'll keep trying

Audrey
6/10/2021
6/10/2021

No irritation - good for starting a retinol but I think it could be a little stronger. Nice packaging - easy to use and helpful instructions

Doris
6/10/2021
6/8/2021

I have struggled with my skin for so many years. This has really helped calm down my acne. My skin looks brighter, and my pores smaller. I have not had the huge breakouts I have had in the past. I am hopefully that I will continue to see these results...if so I will be a customer for life!

Pamela
6/8/2021
6/8/2021

this medication has cleared my skin up nicely.

Ashley
6/8/2021
6/8/2021

My daughter started this medicine 2 weeks ago. She started slowly and only applied every 3 days, then every other day, and now is applying 1 time per day. She has very sensitive skin but so far has not experienced any side effects or adverse reaction to the medication.

Adeline
6/8/2021
6/8/2021

I have not seen any change in my skin. Disappointed after I spent this amount of money on such an ineffective, expensive product.

Kelly
6/8/2021
6/6/2021

seems to be working fine but the percentage of tretinoin is lower than what I have used in the past

Tynisha
6/6/2021