Apostrophe Oral medication and topical medication bottles stacked on shapes
Apostrophe Oral medication and topical medication bottles stacked on shapes
Apostrophe Oral medication and topical medication bottles stacked on shapes

Topical and oral medications custom curated by your dermatology team.

Explore our treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

Our custom topical formula comes packed with prescription-grade ingredients in a moisturizing lotion with aloe and vitamin E. Apostrophe’s topical medication blends seamlessly into your skincare routine– no more weird goopy aluminum tubes. All that tailored to you by your expert dermatology team.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. We offer the widest range of prescription ingredients and strengths so we can create the formula that’s perfect for your skin. From the most sensitive skin to the most severe acne, our custom treatments have you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

Our nourishing texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Apostrophe Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Orals are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your provider will only prescribe these if they feel you’ll get better results.

Learn more about our antibiotics

Hormonal treatment

These treatments are for women who experience jawline breakouts that are caused by hormonal imbalances. Your provider will only prescribe this if they feel you’re a good candidate.

Learn more about our hormonal treatments

Better, together.

Your Apostrophe treatment plan may contain several of these acne medications. Your dermatology provider will curate your customized treatment plan so you can get the best results.

“Acne medications work best in combination since we’re able to fight acne from different angles. Only topical treatments target the root cause of acne, the clogged pore, but oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Aimee paik, md

Real patients,
real results.

Read reviews of our topical and oral medications below.

5.00/5 based on 5 reviews.
Caret iconBlack upwards facing triangle to reference things above or scroll to the top of page.
Caret iconBlack upwards facing triangle to reference things above or scroll to the top of page.
985 reviews
6/8/2022

I was unsure what to expect out of such a strong formula, but so far (3 weeks in) I have had no negative reactions. My skin is really sensitive and I struggle with redness, and it has helped tone down the redness when I wake up in the mornings. I have intermittent issues with the vacuum pump, but it eventually always comes up with something...haha. I also was prescribed half a pump for my whole face but that never seems to go far enough, so I really just target my problem areas so that I have enough to last.

Sarah
6/8/2022
6/8/2022

Noticeable improvement in week 3. My hopes are high now as I really see lights at the end of the tunnel this time. Will keep at it.

Sixu
6/8/2022
6/8/2022

I was using a different Tret mix before until I asked for one with Azelaic Acid. All I can say is WOW. My skin is glistening and I've been getting compliments on my skin that I haven't had since before my major breakout last year that left extreme scarring. I use this mix and added in 6% Hydroquinone and my stubborn hyperpigmentation scars are finally clearing up! The prior Tret mix I had + the hydroquinone was moving a lot slower for me and I still had some reoccurring cystic acne. But now with the Azelaic Acid? Huge difference! I'm not the one to write reviews and I am a skeptic of most skin products but this brand is amazing. They saved my skin and my self esteem. I used to cry seeing my face in the mirror after trying $1,000 worth of many products (seriously!) with no success. My friend recommended I finally look into Tret and I researched until I found Apostrophe. Best decision ever and I thought I would never find anything to help me until now. I highly recommend. The customer service is amazing and they have a very quick turnaround. For the team reading this, please don't ever change this formula. I want to use this for the rest of my life! Thank you so much!

Sanina
6/8/2022
6/8/2022

I am noticing improvements every week with my skin. I feel more confident in my skin. My acne diminished and my hyperpigmentation. The only thing that is preventing me from giving this formula five stars is that I still have some hyperpigmentation. I will wait to see if it clears up over time but I do hope that it completely clears.

Veronica
6/8/2022
6/7/2022

I have fought acne my whole life and melasma since 2014. After several failed attempts to get treatment through my hmo consistently, I found Apostrophe. A simple but thorough medical questionnaire got me to a familiar treatment plan that has already begun to show progress. So thankful for this company.

Amy
6/7/2022
6/6/2022

Such a good formula, and such a convenient service! One thing to note is that sometimes your skin starts out red and angry when you first put it on, which makes the hyperpigmentation look once, but keep at it and that fades and your skin gets used to it, then landing on the fascinating next phase - peeling! (Seriously, more peeling than retinoids) But then the hyperpigmentation goes away, and it's lovely. Looking forward to trying it on a few pesky freckles. Thanks Apostrophe!

Bettina
6/6/2022
6/6/2022

I've been using this in conjunction with oral route spironolactone, and it seems to be helping to keep my hormonal cystic acne at bay. It does smell a little funny but it's not a huge problem.

Adrianna-marie
6/6/2022
6/2/2022

Using Apostrophe was so easy. My medication arrived quickly and I appreciated the additional information provided to me about my skin.

Jill
6/2/2022
6/2/2022

This formula has been working very well for my skin. It is non-irritating, and I've noticed a reduction in my breakouts and dark marks. I wish the bottle pumped the formula out a little smoother, but the overall product has been great for my skin. I'm excited to continue using it!

Lea
6/2/2022
6/1/2022

This clears up my skin oils and prevents the painful, cystic acne around my jawline I've been struggling with.

Mikaela
6/1/2022