Topical and oral medications custom curated by your dermatologist.

Explore our treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

Our proprietary custom topical formula comes packed with prescription-grade ingredients in a moisturizing lotion with 4% niacinamide, aloe and vitamin E. Apostrophe’s topical medication blends seamlessly into your skincare routine– no more weird goopy aluminum tubes. All that tailored to you by your board-certified dermatologist.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. We offer the widest range of prescription ingredients and strengths so our doctors can create the formula that’s perfect for your skin. From the most sensitive skin to the most severe acne, our custom topical formula has you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

Our nourishing texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Apostrophe Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Orals are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your doctor will only prescribe these if they feel you’ll get better results.

Learn more about our antibiotics

Hormonal treatment

This treatment is for women who experience jawline breakouts that are caused by hormonal imbalances. Your doctor will only prescribe this if they feel you’re a good candidate.

Learn more about our hormonal treatments

Better, together.

Your Apostrophe treatment plan may contain several of these power-packed medications. Your dermatologist will design your medication to work synergistically together so you can get the best possible outcomes.

“Acne medications work best in combination since we’re able to fight acne from different angles. Only topical treatments target the root cause of acne, the clogged pore, but oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Aimee paik, md

Real Patients,
real results.

Read reviews of our topical and oral medications below.

5.00/5 based on 5 reviews.
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709 reviews
7/30/2021

This stuff smells like onions or food cooking. Not my favorite thing to put on my face. I've used a topical spironolactone from a custom compounding pharmacy in the past that had no smell so I wonder if this could be improved. In addition, my first shipment of this formula was super grainy. Customer service fixed it right away so I did not deduct any more stars from the rating. I feel that it has been helping clear up my acne.

Anna
7/30/2021
7/30/2021

Helps to calm my face but acne still present 2+ weeks later.

Nicole
7/30/2021
7/30/2021

Seems to be helping acne somewhat, but side effect of diarrhea

Nicole
7/30/2021
7/29/2021

My facial patch is still there and not fading as I expected Will continue to use for a few more weeks and see! Thanks Ram

Chennai
7/29/2021
7/28/2021

This is the first time I have had Apostrophe Tretinoin with Niacinamide formula. I have been using it for a couple of weeks and can say I do not like it as much as my previous Tretinoin prescription. This has a very lotion like consistency and I prefer a cream consistency. I am also getting more peeling with this very then my previous although they are the same strength.

Shelley
7/28/2021
7/28/2021

For hormonal acne, it's the only thing that works for me!

Destr
7/28/2021
7/27/2021

My Melasma for the first time is fading. The only reason I did not give it 5 stars is because i am not totally sure if this product is the reason for the fading or if it's the Retin A.

Cimarron Wolf
7/27/2021
7/27/2021

It's done wonders for my skin on my face and my butt/upper thigh areas. And it was very fast acting and a lot of the scarring on my butt has also gone away. 10/10

Sudie
7/27/2021
7/27/2021

Not only is my skin discoloration starting to lighten, the texture of my skin is also changing. It looks much better. My wrinkles are smoothing a bit in just a short time and my top layer of skin has been slowly exfoliating. I have used so many products over the years only to be discouraged, but for the first time I seeing results.

Cimarron Wolf
7/27/2021
7/26/2021

One thing is too see the transformation, the other is to have others tell you. I'm on my 1st month and while there have been challenges adjusting to the medication, my skin has gradually improved and is taking on the medication at least 4x a week. I started with 2.

Marisol
7/26/2021