Sulfamethoxazole-TrimethoprimAn oral antibiotic with anti-inflammatory effects.Sulfamethoxazole-TrimethoprimOral MedicationTrueWomen who are pregnant should not use this medication.tabletanti-bacterial sulfonamidePrescription160-800mg

Trimethoprim-sulfamethoxazole in acne vulgaris: a double-blind study.

Dermatologica

A double-blind, crossover trial involving 43 patients demonstrated that trimethoprim-sulfamethoxazole 80/400mg given once daily produced a statistically significant improvement in acne over placebo.

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Oral trimethoprim-sulfamethoxazole in the treatment of acne vulgaris.

Cutis

A review of the use of trimethoprim-sulfamethoxazole in the treatment of acne concluded it should be used judiciously and reserved for those who have failed other antibiotic therapies.

`

A comparison of low dosage trimethoprim/sulfamethoxazole with oxytetracycline in acne vulgaris.

Cutis

A double-blind study demonstrated that trimethoprim/sulfamethoxazole is an equally safe and effective therapeutic agent as oxytetracycline.

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Oral Spironolactone in Post-teenage Female Patients with Acne Vulgaris

Journal of Drugs in Dermatology

A review of the use of systemic antibiotics for acne describes trimethoprim-sulfamethoxazole as a relatively safe and successful third-line agent in refractory cases of acne.

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Comparative analysis of adverse drug reactions to tetracyclines: results of a French national survey and review of the literature.

Journal of the American Academy of Dermatology

The use of trimethoprim-sulfamethoxazole for acne should be restricted to patients who are unable to tolerate tetracyclines or in treatment-resistant patients.

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IngredientsSulfamethoxazole-Trimethoprim

Sulfa

Oral Medication

C24H29N7O6S

Oral medication icon clear backgroundBlack, pill shaped outline with white background.

TARGETS:

Inflammation IconBlack like with a bump in the middle and a copy of that bump offset above the line.

Inflammation

BENEFITS:

Improves moderate-to-severe acne

Reduces acne located on the chest and back

Helps get active lesions under control while topical treatments kick in

1972

Trimethoprim-sulfamethoxazole in acne vulgaris: a double-blind study.

Dermatologica

2007

Oral trimethoprim-sulfamethoxazole in the treatment of acne vulgaris.

Cutis

1980

A comparison of low dosage trimethoprim/sulfamethoxazole with oxytetracycline in acne vulgaris.

Cutis

2007

Oral Spironolactone in Post-teenage Female Patients with Acne Vulgaris

Journal of Drugs in Dermatology

2016

Comparative analysis of adverse drug reactions to tetracyclines: results of a French national survey and review of the literature.

Journal of the American Academy of Dermatology

Horizontal scroll arrowsTwo black arrows facing opposite directions on top of one another to signify the ability to scroll left and right.

SIDE EFFECTS


Common side effects include nausea, diarrhea, loss of appetite, mild itching and rash. Oral thrush or vaginal yeast infections can occur with prolonged use. Long-term use can also cause a decrease in blood cell counts. This drug may rarely cause a severe drug rash called Stevens-Johnson syndrome or toxic epidermal necrolysis. You should stop this medication immediately if you develop sores in the eyes, mouth or genital area or a severe rash. Allergic reaction to this medication is rare. Symptoms of an allergic reaction include rash, itching/swelling (especially of face/tongue/throat), dizziness and trouble breathing. You should not use this medication if you have severe liver or kidney disease or anemia caused by folic acid deficiency. Women who are pregnant should not use this medication.

This is not a complete list of side effects and others may occur. Contact your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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