Journal of Dermatological Treatment

Use of nicotinamide in dermatology

Journal of Dermatological Treatment

A review article highlighting the use of nicotinamide (niacinamide) in dermatology and their supporting clinical studies.

2017

https://onlinelibrary.wiley.com/doi/full/10.1111/ced.13021

Journal of the Turkish Academy of Dermatology

An investigation of efficacy of topical niacinamide for the treatment of mild and moderate acne vulgaris.

Journal of the Turkish Academy of Dermatology

Use of a niacinamide 4% gel significantly reduced the number of comedones, papules and pustules after 8 weeks as compared to the onset of treatment.

2008

http://www.jtad.org/2008/4/jtad82402a.pdf

Dermatologic Surgery

Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance

Dermatologic Surgery

In a 12-week, split-face, vehicle-controlled study, niacinamide 5% significantly improved fine lines and wrinkles, hyperpigmented spots, red blotchiness, skin sallowness and elasticity over the control.

2006

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1524-4725.2005.31732

Journal of Cosmetic and Laser Therapy

The effect of 2% niacinamide on facial sebum production.

Journal of Cosmetic and Laser Therapy

In a double-blind, placebo-controlled study, niacinamide 2% decreased sebum excretion rates in Japanese subjects after 2 and 4 weeks of application compared to the control group. In Caucasian subjects, casual sebum levels were reduced after 6 wks of use compared to the control group.

2006

https://www.tandfonline.com/doi/abs/10.1080/14764170600717704

Cutis

Niacinamide-containing Facial Moisturizer Improves Skin Barrier and Benefits Subjects with Rosacea.

Cutis

A niacinamide 2% facial moisturizer significantly improved skin barrier function and hydration when used on the forearm twice daily for 4 wks.

2005

https://pdfs.semanticscholar.org/c866/417320abb8a6d79791d10ad66c6acc6b22d2.pdf

International Journal of Cosmetic Science

Topical niacinamide reduces yellowing, wrinkling, red blotchiness and hyperpigmented spots in aging facial skin.

International Journal of Cosmetic Science

In a 12-week, split-face, vehicle-controlled study, niacinamide 5% significantly improved fine lines/wrinkles, hyperpigmentation spots, texture, red blotchiness and skin yellowing (sallowness) over the control.

2004

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1467-2494.2004.00228.x

British Journal of Dermatology

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.

British Journal of Dermatology

In clinical studies, niacinamide significantly decreased hyperpigmentation over the vehicle after 4 weeks of use.

2002

https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2133.2002.04834.x

International Journal of Dermatology

Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris.

International Journal of Dermatology

Nicotinamide 4% was as effective as clindamycin 1% at reducing inflammatory acne after twice daily use for 8 weeks.

1995

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-4362.1995.tb04449.x