Medically reviewed by Aimee Paik, MD
Written by Apostrophe Team
Last updated 1/3/2023
You may have noticed an interesting difference in Apostrophe’s prescription acne treatments compared to the medications you pick-up at your pharmacy: many of our topical formulations compound multiple active prescription ingredients combined in a single bottle. We asked Apostrophe’s medical director, Dr. Aimee Paik, about the benefits of combining ingredients and how mixing these meds help you get clear skin fast.
Tretinoin + Clindamycin – While tretinoin is very effective at addressing acne and fine lines and wrinkles when used alone, it is given a boost when combined with clindamycin. Clindamycin is an antibiotic that targets the inflammation and redness that accompany inflammatory acne. Like tretinoin, clindamycin can be very effective against acne when used alone. Dr. Paik notes, “We combined clindamycin and tretinoin to enhance efficacy and to make it a cost-effective option for patients.” That means more effective treatment with two power-house ingredients for a lower cost. It’s a win-win!
Clindamycin + Benzoyl peroxide – Clindamycin is an antibiotic and as such, it is possible for any acne-causing bacteria on your face to develop resistance to it. Dr. Paik says, “Clindamycin is combined with benzoyl peroxide to help with efficacy and to prevent antibiotic resistance. This combination makes clindamycin more effective and allows it to stay effective over time.” Since benzoyl peroxide keeps resistance from developing, the clindamycin can work longer and harder for you!
Niacinamide – A number of our topicals include niacinamide because it is the closest thing in skincare to a cure-all! Dr. Paik’s thoughts on this useful treatment: “Our medications are combined with niacinamide to help with inflammation, reduce redness, and prevent post-inflammatory hyperpigmentation.” Many acne-fighting medications like tretinoin or clindamycin can cause dryness and irritation. Niacinamide helps soothe and calm the skin so you look your best while your treatments get to work busting those breakouts.
Some ingredients can form beautiful partnerships. Compounding ingredients together can help increase efficacy and decrease cost. It’s the best of both worlds!
Have questions about Apostrophe’s acne treatments? Wondering how to maximize the results of your skincare routine? Ask us on Twitter @hi_apostrophe.
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