Topical spironolactone is a medication used to treat acne. Topical spironolactone is particularly effective for treating hormonal acne for everyone, regardless of sex, gender, or sensitivity to oral medications.
Topical spironolactone reduces acne and decreases oily skin. It’s safe to use for all genders (unlike oral spironolactone which is typically not prescribed to cisgender or trans men for hormonal acne.)
What is the difference between topical spironolactone and oral spironolactone for acne?
Oral spironolactone works from the inside out to prevent hormonal acne but some people can’t tolerate the side effects that may come with it. Topical spironolactone can be a good solution that doesn’t cause these same systemic side effects but can help with hormonal causes of acne at the skin level. It can also be used with oral spironolactone to reduce the amount of oral spironolactone needed.
How to treat hormonal acne?
Androgens play a major role in all types of acne in both men and women. Dermatologists often treat hormonal acne in women with oral contraceptive pills or spironolactone which counter the effects of androgens. Due to systemic side effects, men are not eligible for treatment with these oral medications. Spironolactone in a topical form is an innovative treatment that doesn’t have systemic effects and can help acne in both men and women. It can be used in all ranges of acne severity.
Can men use spironolactone?
Oral spironolactone can’t be used by men since it’s disruptive to their hormones. However, men can use topical spironolactone because it has no systemic hormonal side effects and does not affect male hormones.
How to use a spironolactone cream?
How do I get topical spironolactone?
If you want to treat your acne with topical spironolactone, the best place to go is Apostrophe. With Apostrophe, you will receive an online dermatology consultation to make sure topical spironolactone is right for you, and then you will get a custom formulated prescription sent to your home. Your topical spironolactone cream may be formulated with other acne fighting ingredients like tretinoin, clindamycin, or tranexamic acid.
Does topical spironolactone really work for acne?
Topical spironolactone is shown to decrease oil production which can help effectively treat acne. In both men and women topical spironolactone has been shown to improve acne in 95% of study participants in just one month. Topical spironolactone has no systemic side effects on male hormones , so men can safely use topical spironolactone as a helpful adjunctive treatment.
We recommend to use topical spironolactone with other acne fighting treatments like tretinoin, clindamycin. You can also use it with tranexamic acid to help fight dark and red marks left over from breakouts. Combining these ingredients creates a powerful prescription that fights acne in multiple ways.
Side effects of spironolactone cream:
The most common are redness, peeling, and skin sensitivity, so it’s best to ease into treatment. Your skin will adjust to the medication over time.
Oral spironolactone acts as a diuretic and can cause increased urination, headaches, dizziness and high potassium levels in susceptible individuals. Oral spironolactone also has hormonal effects and can cause menstrual spotting, breast tenderness and can potentially cause birth defects.Topical spironolactone is not absorbed into the blood and will not cause these systemic side effects.
Warnings when taking topical spironolactone:
If you become pregnant while taking this medication, discontinue use immediately and message your doctor for an alternative.
Be sure to apply sunscreen every morning with at least SPF 30. This formula can make your skin more sensitive to the sun, especially during the first six months of use. Avoid direct sun exposure, tanning beds, and sun lamps.