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Ingredients → Tranexamic Acid
TXA
Topical Medication
C20H28O2
TARGETS:
Inhibits melanin synthesis.
Reduces redness and decreases abnormal blood vessels.
BENEFITS:
→
Improves moderate-to-severe melasma.
→
Improves melasma that does not respond to other treatments.
2019
Topical 5% tranexamic acid for acne-related postinflammatory erythema.
JAAD
2019
Clinical evaluation of a facial serum containing 3% tranexamic acid on women with mild to moderate skin pigmentation conditions
...
Journal of the American Academy of Dermatology
2018
Randomized, placebo-controlled, double-blind study of oral tranexamic acid in the treatment of moderate-to-severe melasma
...
JAAD
2016
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis
...
JAAD
2012
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis
...
JEADV
SIDE EFFECTS
The most common side effects include stomach upset, nausea, changes in menstrual periods (lighter or absent periods), headache, muscle aches, joint pain, muscle cramps, migraine, and fatigue. This medication should not be taken if you are pregnant or breastfeeding. This medication may increase the risk of blood clots. Stop this medication and seek medical attention if you develop swelling in one or both legs, difficulty breathing, eye symptoms or changes in vision. If you develop vision changes, you should see an ophthalmologist immediately for evaluation, including a dilated retinal examination. Do not take this medication if you suspect you have COVID-19. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of side effects and others may occur. Contact your dermatology provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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